Adaptive islet biology and incretin physiology provide a framework linking diverse diabetes phenotypes, with advances in β-cell stress adaptation, intra-islet communication, receptor-resolved biology, and β-cell mass imaging. By integrating clinical perspectives from Asia and Europe with multiscale islet-cell biology, these insights may support mechanism-based and more targeted therapeutic approaches.
Journal article
2026-06-01T00:00:00+00:00
Department of Diabetes, Endocrinology and Nutrition, Kyoto University Graduate School of Medicine, Kyoto, Japan.